产品货号：
Z15546
中文名称：
DFF45/DFFA抗体
英文名称：
Anti-DFF45/DFFA Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DFF45/DFFA Antibody |
| 指标别名 | DFF 45;DFF1;DFF45;DFF45/DFFA;DFFA;ICAD;Inhibitor of CAD |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | DFFA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from the Internal region of human ICAD.at AA rangle:120-200 |
| 计算分子量 | 37KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | Immunogen affinity purified |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | DNA fragmentation factor subunit alpha (DFFA),also known as Inhibitor of caspase-activated DNase (ICAD),is a protein that in humans is encoded by the DFFA gene.Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development.The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units.DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits.DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis.DFF becomes activated when DFFA is cleaved by caspase-3.The cleaved fragments of DFFA dissociate from DFFB,the active component of DFF.DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis.Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Uniprot ID | O00273 |
| 基因名全称 | DNA fragmentation factor subunit alpha |
| 推荐稀释比 | WB,1:500～1:2000 |
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